Concentration-Dependent Antagonism and Culture Conversion in Pulmonary Tuberculosis

BACKGROUND. There is scant evidence to support target drug exposures for optimal tuberculosis outcomes. We therefore assessed whether pharmacokinetic/pharmacodynamic (PK/PD) parameters could predict 2-month culture conversion. METHODS. One hundred patients with pulmonary tuberculosis (65% human immu...

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Bibliographic Details
Published in:Clin Infect Dis
Main Authors: Rockwood, Neesha, Pasipanodya, Jotam G., Denti, Paolo, Sirgel, Frederick, Lesosky, Maia, Gumbo, Tawanda, Meintjes, Graeme, McIlleron, Helen, Wilkinson, Robert J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Major Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411399/
https://ncbi.nlm.nih.gov/pubmed/28205671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cix158
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