HIV-1 Coinfection Does Not Reduce Exposure to Rifampin, Isoniazid, and Pyrazinamide in South African Tuberculosis Outpatients

There are contrasting data in the literature about antituberculosis plasma drug concentrations in HIV-1-coinfected patients. We report the pharmacokinetics of rifampin, isoniazid, and pyrazinamide in a cohort of patients being treated for active tuberculosis, the majority of whom were coinfected wit...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Rockwood, Neesha, Meintjes, Graeme, Chirehwa, Maxwell, Wiesner, Lubbe, McIlleron, Helen, Wilkinson, Robert J., Denti, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038257/
https://ncbi.nlm.nih.gov/pubmed/27480859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00480-16
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