Population Pharmacokinetics of Rifampin in Pregnant Women with Tuberculosis and HIV Coinfection in Soweto, South Africa

Effective treatment of tuberculosis during pregnancy is essential for preventing maternal and fetal mortality, but little is known about the effects of pregnancy on the disposition of antituberculosis drugs. We explored the effects of pregnancy on the pharmacokinetics of rifampin, the key sterilizin...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Denti, Paolo, Martinson, Neil, Cohn, Silvia, Mashabela, Fildah, Hoffmann, Jennifer, Msandiwa, Reginah, Castel, Sandra, Wiesner, Lubbe, Chaisson, Richard E., McIlleron, Helen, Dooley, Kelly E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776013/
https://ncbi.nlm.nih.gov/pubmed/26643345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02051-15
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