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C-CBL E3 ubiquitin ligase expression increases across the spectrum of benign and malignant T-cell skin diseases
Prolonged survival of lesional T cells plays a central role in the pathogenesis of T-cell-mediated dermatoses. We have recently shown that the ubiquitin ligase c-CBL is highly expressed in cutaneous T-cell lymphoma (CTCL) and that its knockdown increases activation-induced cell death, a key pathway...
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| Publicado no: | Am J Dermatopathol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5411343/ https://ncbi.nlm.nih.gov/pubmed/27805921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/DAD.0000000000000780 |
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