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Phosphorylation control of the ubiquitin ligase Cbl is conserved in choanoflagellates
Cbl proteins are E3 ubiquitin ligases specialized for the regulation of tyrosine kinases by ubiquitylation. Human Cbl proteins are activated by tyrosine phosphorylation, thus setting up a feedback loop whereby the activation of tyrosine kinases triggers their own degradation. Cbl proteins are target...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5916117/ https://ncbi.nlm.nih.gov/pubmed/29498112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3397 |
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