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c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses

The activation of signalling pathways by ligand engagement with transmembrane receptors is responsible for determining many aspects of cellular function and fate. While these outcomes are initially determined by the nature of the ligand and its receptor, it is also essential that intracellular enzym...

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Detalhes bibliográficos
Main Authors: Thien, Christine B. F., Langdon, Wallace Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276912/
https://ncbi.nlm.nih.gov/pubmed/16212556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050892
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