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E3 ubiquitin ligase Cbl-b in innate and adaptive immunity

Casitas B-lineage lymphoma proto-oncogene-b (Cbl-b), a RING finger E3 ubiquitin-protein ligase, has been demonstrated to play a crucial role in establishing the threshold for T-cell activation and controlling peripheral T-cell tolerance via multiple mechanisms. Accumulating evidence suggests that Cb...

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Detalhes bibliográficos
Main Authors: Liu, Qingjun, Zhou, Hong, Langdon, Wallace Y, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111751/
https://ncbi.nlm.nih.gov/pubmed/24875217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29213
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