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Cbl-b: Roles in T Cell Tolerance, Proallergic T Cell Development, and Cancer Immunity

Cbl-b is a member of the Cbl family of RING finger E3 ubiquitin ligases and polymorphisms and mutations in Cbl-b are associated with several autoimmune/inflammatory diseases in humans. Furthermore, gene targeting experiments in mice have provided proof of the in vivo effects of Cbl-b on T cell funct...

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Bibliographische Detailangaben
Veröffentlicht in:Inflamm Cell Signal
Hauptverfasser: Zhang, Jian, Liu, Qingjun, Langdon, Wallace Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465365/
https://ncbi.nlm.nih.gov/pubmed/26082933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/ics.146
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