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Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks
DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a distinct factor in the non-homologous end-joining (NHEJ) pathway involved in DNA double-strand break (DSB) repair. We examined the crosstalk between key proteins in the DSB NHEJ repair pathway and cell cycle regulation and found that mou...
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| Veröffentlicht in: | Oncotarget |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410253/ https://ncbi.nlm.nih.gov/pubmed/28186989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15153 |
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