Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks

DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a distinct factor in the non-homologous end-joining (NHEJ) pathway involved in DNA double-strand break (DSB) repair. We examined the crosstalk between key proteins in the DSB NHEJ repair pathway and cell cycle regulation and found that mou...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dong, Jun, Zhang, Tian, Ren, Yufeng, Wang, Zhenyu, Ling, Clifton C., He, Fuqiu, Li, Gloria C., Wang, Chengtao, Wen, Bixiu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410253/
https://ncbi.nlm.nih.gov/pubmed/28186989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15153
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