Mycobacterium tuberculosis EsxL inhibits MHC-II expression by promoting hypermethylation in class-II transactivator loci in macrophages

Mycobacterium tuberculosis is known to modulate the host immune responses to facilitate its persistence inside the host cells. One of the key mechanisms includes repression of class-II transactivator (CIITA) and MHC-II expression in infected macrophages. However, the precise mechanism of CIITA and M...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Sengupta, Srabasti, Naz, Saba, Das, Ishani, Ahad, Abdul, Padhi, Avinash, Naik, Sumanta Kumar, Ganguli, Geetanjali, Pattanaik, Kali Prasad, Raghav, Sunil Kumar, Nandicoori, Vinay Kumar, Sonawane, Avinash
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409457/
https://ncbi.nlm.nih.gov/pubmed/28209712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.775205
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki