A Mycobacterial Phosphoribosyltransferase Promotes Bacillary Survival by Inhibiting Oxidative Stress and Autophagy Pathways in Macrophages and Zebrafish

Mycobacterium tuberculosis employs various strategies to modulate host immune responses to facilitate its persistence in macrophages. The M. tuberculosis cell wall contains numerous glycoproteins with unknown roles in pathogenesis. Here, by using Concanavalin A and LC-MS analysis, we identified a no...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Mohanty, Soumitra, Jagannathan, Lakshmanan, Ganguli, Geetanjali, Padhi, Avinash, Roy, Debasish, Alaridah, Nader, Saha, Pratip, Nongthomba, Upendra, Godaly, Gabriela, Gopal, Ramesh Kumar, Banerjee, Sulagna, Sonawane, Avinash
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Molecular Bases of Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505583/
https://ncbi.nlm.nih.gov/pubmed/25825498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.598482
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