A Mycobacterial Phosphoribosyltransferase Promotes Bacillary Survival by Inhibiting Oxidative Stress and Autophagy Pathways in Macrophages and Zebrafish

Mycobacterium tuberculosis employs various strategies to modulate host immune responses to facilitate its persistence in macrophages. The M. tuberculosis cell wall contains numerous glycoproteins with unknown roles in pathogenesis. Here, by using Concanavalin A and LC-MS analysis, we identified a no...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Mohanty, Soumitra, Jagannathan, Lakshmanan, Ganguli, Geetanjali, Padhi, Avinash, Roy, Debasish, Alaridah, Nader, Saha, Pratip, Nongthomba, Upendra, Godaly, Gabriela, Gopal, Ramesh Kumar, Banerjee, Sulagna, Sonawane, Avinash
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505583/
https://ncbi.nlm.nih.gov/pubmed/25825498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.598482
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