A Mycobacterial Phosphoribosyltransferase Promotes Bacillary Survival by Inhibiting Oxidative Stress and Autophagy Pathways in Macrophages and Zebrafish

Mycobacterium tuberculosis employs various strategies to modulate host immune responses to facilitate its persistence in macrophages. The M. tuberculosis cell wall contains numerous glycoproteins with unknown roles in pathogenesis. Here, by using Concanavalin A and LC-MS analysis, we identified a no...

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Gepubliceerd in:J Biol Chem
Hoofdauteurs: Mohanty, Soumitra, Jagannathan, Lakshmanan, Ganguli, Geetanjali, Padhi, Avinash, Roy, Debasish, Alaridah, Nader, Saha, Pratip, Nongthomba, Upendra, Godaly, Gabriela, Gopal, Ramesh Kumar, Banerjee, Sulagna, Sonawane, Avinash
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2015
Onderwerpen:
Molecular Bases of Disease
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505583/
https://ncbi.nlm.nih.gov/pubmed/25825498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.598482
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