The subcellular localization of neuronal nitric oxide synthase determines the downstream effects of NO on myocardial function

AIMS: In healthy hearts, the neuronal nitric oxide synthase (nNOS) is predominantly localized to the sarcoplasmic reticulum (SR), where it regulates the ryanodine receptor Ca(2+ )release channel (RyR2) and phospholamban (PLB) phosphorylation, and to a lesser extent to the sarcolemmal membrane where...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cardiovasc Res
Auteurs principaux: Carnicer, Ricardo, Suffredini, Silvia, Liu, Xing, Reilly, Svetlana, Simon, Jillian N., Surdo, Nicoletta C., Zhang, Yin H., Lygate, Craig A., Channon, Keith M., Casadei, Barbara
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408949/
https://ncbi.nlm.nih.gov/pubmed/28158509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx002
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires