The subcellular localization of neuronal nitric oxide synthase determines the downstream effects of NO on myocardial function

AIMS: In healthy hearts, the neuronal nitric oxide synthase (nNOS) is predominantly localized to the sarcoplasmic reticulum (SR), where it regulates the ryanodine receptor Ca(2+ )release channel (RyR2) and phospholamban (PLB) phosphorylation, and to a lesser extent to the sarcolemmal membrane where...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Cardiovasc Res
Glavni autori: Carnicer, Ricardo, Suffredini, Silvia, Liu, Xing, Reilly, Svetlana, Simon, Jillian N., Surdo, Nicoletta C., Zhang, Yin H., Lygate, Craig A., Channon, Keith M., Casadei, Barbara
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408949/
https://ncbi.nlm.nih.gov/pubmed/28158509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx002
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items