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Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling

BACKGROUND: Nitric oxide synthase uncoupling occurs under conditions of oxidative stress modifying the enzyme's function so it generates superoxide rather than nitric oxide. Nitric oxide synthase uncoupling occurs with chronic pressure overload, and both are ameliorated by exogenous tetrahydrob...

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Detaylı Bibliyografya
Yayımlandı:J Am Heart Assoc
Asıl Yazarlar: Hashimoto, Toru, Sivakumaran, Vidhya, Carnicer, Ricardo, Zhu, Guangshuo, Hahn, Virginia S., Bedja, Djahida, Recalde, Alice, Duglan, Drew, Channon, Keith M., Casadei, Barbara, Kass, David A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943286/
https://ncbi.nlm.nih.gov/pubmed/27001967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003208
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