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Dexamethasone, tetrahydrobiopterin and uncoupling of endothelial nitric oxide synthase
OBJECTIVE: To find out whether dexamethasone induces an uncoupling of the endothelial nitric oxide synthase (eNOS). METHODS & RESULTS: A major cause of eNOS uncoupling is a deficiency of its cofactor tetrahydrobiopterin (BH(4)). Treatment of human EA.hy 926 endothelial cells with dexamethasone d...
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Publicado no: | J Geriatr Cardiol |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Science Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4605949/ https://ncbi.nlm.nih.gov/pubmed/26512245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11909/j.issn.1671-5411.2015.05.013 |
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