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A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self‐renewal

The intestinal epithelium is the fastest regenerative tissue in the body, fueled by fast‐cycling stem cells. The number and identity of these dividing and migrating stem cells are maintained by a mosaic pattern at the base of the crypt. How the underlying regulatory scheme manages this dynamic stem...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Chen, Kai‐Yuan, Srinivasan, Tara, Tung, Kuei‐Ling, Belmonte, Julio M, Wang, Lihua, Murthy, Preetish Kadur Lakshminarasimha, Choi, Jiahn, Rakhilin, Nikolai, King, Sarah, Varanko, Anastasia Kristine, Witherspoon, Mavee, Nishimura, Nozomi, Glazier, James A, Lipkin, Steven M, Bu, Pengcheng, Shen, Xiling
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408779/
https://ncbi.nlm.nih.gov/pubmed/28455349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167324
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