Unbiased metabolite profiling indicates that a diminished thymidine pools is the underlying mechanism of colon cancer chemoprevention by alpha-difluoromethylornithine (DFMO)

Por Witherspoon, Mavee, Chen, Qiuying, Kopelovich, Levy, Gross, Steven S., Lipkin, Steven
Publicado em 2013

Mutagenesis Analysis of a Conserved Region Involved in Acetyl Coenzyme A Binding in the Aminoglycoside 6′-N-Acetyltransferase Type Ib Encoded by Plasmid pJHCMW1

Por Pourreza, Atousa, Witherspoon, Mavee, Fox, Jessica, Newmark, Jason, Bui, Duyen, Tolmasky, Marcelo E.
Publicado em 2005

Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells

Por Benoit, Yannick D., Laursen, Kristian B., Witherspoon, Mavee S., Lipkin, Steven M., Gudas, Lorraine J.
Publicado em 2013

Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer

Por Edwards, Robert A., Witherspoon, Mavee, Wang, Kehui, Afrasiabi, Kambiz, Pham, Trang, Birnbaumer, Lutz, Lipkin, Steven M.
Publicado em 2009

The Aminoglycoside 6′-N-Acetyltransferase Type Ib Encoded by Tn1331 Is Evenly Distributed within the Cell's Cytoplasm

Por Dery, Ken J., Søballe, Britta, Witherspoon, Mavee S. L., Bui, Duyen, Koch, Robert, Sherratt, David J., Tolmasky, Marcelo E.
Publicado em 2003

Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells

Por Benoit, Yannick D., Witherspoon, Mavee S., Laursen, Kristian B., Guezguez, Amel, Beauséjour, Marco, Beaulieu, Jean-Francois, Lipkin, Steven M., Gudas, Lorraine J.
Publicado em 2013

Colonic Organoids Derived from Human Pluripotent Stem Cells for Modeling Colorectal Cancer and Drug Testing

Por Crespo, Miguel, Vilar, Eduardo, Tsai, Su-Yi, Chang, Kyle, Amin, Sadaf, Srinivasan, Tara, Zhang, Tuo, Pipalia, Nina H, Chen, Huanhuan Joyce, Witherspoon, Mavee, Gordillo, Miriam, Xiang, Jenny Zhaoying, Maxfield, Frederick R., Lipkin, Steven, Evans, Todd, Chen, Shuibing
Publicado no Nat Med (2017)

A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self‐renewal

Por Chen, Kai‐Yuan, Srinivasan, Tara, Tung, Kuei‐Ling, Belmonte, Julio M, Wang, Lihua, Murthy, Preetish Kadur Lakshminarasimha, Choi, Jiahn, Rakhilin, Nikolai, King, Sarah, Varanko, Anastasia Kristine, Witherspoon, Mavee, Nishimura, Nozomi, Glazier, James A, Lipkin, Steven M, Bu, Pengcheng, Shen, Xiling
Publicado no Mol Syst Biol (2017)

A microRNA miR-34a Regulated Bimodal Switch targets Notch in Colon Cancer Stem Cells

Por Bu, Pengcheng, Chen, Kai-Yuan, Chen, Joyce Huan, Wang, Lihua, Walters, Jewell, Shin, Yong Jun, Goerger, Julian P., Sun, Jian, Witherspoon, Mavee, Rakhilin, Nikolai, Li, Jiahe, Yang, Herman, Milsom, Jeff, Lee, Sang, Zipfel, Warren, Jin, Moonsoo M., Gümüşcedil, Zeynep H., Lipkin, Steven M., Shen, Xiling
Publicado em 2013