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A microRNA miR-34a Regulated Bimodal Switch targets Notch in Colon Cancer Stem Cells
microRNAs regulate developmental cell fate decisions, tissue homeostasis and oncogenesis in distinct ways relative to proteins. Here, we show that the tumor suppressor microRNA miR-34a is a cell fate determinant in early stage dividing colon cancer stem cells (CCSCs). In pair-cell assays, miR34a dis...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646336/ https://ncbi.nlm.nih.gov/pubmed/23642368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.03.002 |
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