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A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division

The roles of long non-coding RNAs (lncRNAs) in regulating cancer and stem cells are being increasingly appreciated. Its diverse mechanisms provide the regulatory network with a bigger repertoire to increase complexity. Here we report a novel LncRNA, Lnc34a, that is enriched in colon cancer stem cell...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Wang, Lihua, Bu, Pengcheng, Ai, Yiwei, Srinivasan, Tara, Chen, Huanhuan Joyce, Xiang, Kun, Lipkin, Steven M, Shen, Xiling
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859802/
https://ncbi.nlm.nih.gov/pubmed/27077950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14620
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