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FoxO3 increases miR-34a to cause palmitate-induced cholangiocyte lipoapoptosis

Nonalcoholic steatohepatitis (NASH) patients have elevated plasma saturated free fatty acid levels. These toxic fatty acids can induce liver cell death and our recent results demonstrated that the biliary epithelium may be susceptible to lipotoxicity. Here, we explored the molecular mechanisms of ch...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Lipid Res
मुख्य लेखकों: Natarajan, Sathish Kumar, Stringham, Bailey A., Mohr, Ashley M., Wehrkamp, Cody J., Lu, Sizhao, Phillippi, Mary Anne, Harrison-Findik, Dee, Mott, Justin L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Biochemistry and Molecular Biology 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408604/
https://ncbi.nlm.nih.gov/pubmed/28250026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M071357
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