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XIAP Antagonist Embelin Inhibited Proliferation of Cholangiocarcinoma Cells

Cholangiocarcinoma cells are dependent on antiapoptotic signaling for survival and resistance to death stimuli. Recent mechanistic studies have revealed that increased cellular expression of the E3 ubiquitin-protein ligase X-linked inhibitor of apoptosis (XIAP) impairs TRAIL- and chemotherapy-induce...

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Detalhes bibliográficos
Main Authors: Wehrkamp, Cody J., Gutwein, Ashley R., Natarajan, Sathish Kumar, Phillippi, Mary Anne, Mott, Justin L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946004/
https://ncbi.nlm.nih.gov/pubmed/24603802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090238
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