XIAP Antagonist Embelin Inhibited Proliferation of Cholangiocarcinoma Cells

Cholangiocarcinoma cells are dependent on antiapoptotic signaling for survival and resistance to death stimuli. Recent mechanistic studies have revealed that increased cellular expression of the E3 ubiquitin-protein ligase X-linked inhibitor of apoptosis (XIAP) impairs TRAIL- and chemotherapy-induce...

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Autores principales: Wehrkamp, Cody J., Gutwein, Ashley R., Natarajan, Sathish Kumar, Phillippi, Mary Anne, Mott, Justin L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946004/
https://ncbi.nlm.nih.gov/pubmed/24603802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090238
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