Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway

Changes in lipid metabolism and iron content are observed in the livers of patients with fatty liver disease. The expression of hepcidin, an iron-regulatory and acute phase protein synthesized by the liver, is also modulated. The potential interaction of lipid and iron metabolism is largely unknown....

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Bibliographic Details
Published in:PLoS One
Main Authors: Lu, Sizhao, Natarajan, Sathish Kumar, Mott, Justin L., Kharbanda, Kusum K., Harrison-Findik, Duygu Dee
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726556/
https://ncbi.nlm.nih.gov/pubmed/26807955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147474
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