Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway

BACKGROUND: Nonalcoholic fatty liver disease is one of the most common liver diseases in the world and is a typical hepatic manifestation of metabolic syndrome which is characterized with lipid accumulation in liver. Nicotinamide phosphoribosyltransferase (NAMPT) has been recently identified as an e...

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Wang, Ling-Fang, Wang, Xiao-Nv, Huang, Cong-Cong, Hu, Long, Xiao, Yun-Fei, Guan, Xiao-Hui, Qian, Yi-Song, Deng, Ke-Yu, Xin, Hong-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408374/
https://ncbi.nlm.nih.gov/pubmed/28449683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-017-0464-z
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