JAZF1 ameliorates age and diet-associated hepatic steatosis through SREBP-1c -dependent mechanism

JAZF zinc finger 1 (JAZF1) is involved in glucose and lipid metabolisms. However, its role in aging- and nutrient-related hepatic steatosis is unclear. In the current study, we demonstrated that JAZF1 expression was markedly down-regulated in obesity-associated mice and nonalcoholic fatty liver dise...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Wei, Qin, Zhou, Baoyong, Yang, Gangyi, Hu, Wenjing, Zhang, Lili, Liu, Rui, Li, Minyan, Wang, Kuan, Gu, Harvest F., Guan, Youfei, Zhu, Zhiming, Zheng, Hongting, Peng, Jun, Li, Ling
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113258/
https://ncbi.nlm.nih.gov/pubmed/30154417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0923-0
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