Vaccine elicitation of high mannose-dependent neutralizing antibodies against the V3-glycan broadly neutralizing epitope in nonhuman primates

Induction of broadly neutralizing antibodies (bnAbs) that target HIV-1 envelope (Env) is a goal of HIV-1 vaccine development. A bnAb target is the Env third variable loop (V3)-glycan site. To determine if immunization could induce antibodies to the V3-glycan bnAb binding site, we repetitively immuni...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Saunders, Kevin O., Nicely, Nathan I., Wiehe, Kevin J., Bonsignori, Mattia, Meyerhoff, R. Ryan, Parks, Robert, Walkowicz, William E., Aussedat, Baptiste, Wu, Nelson R., Cai, Fangping, Vohra, Yusuf, Park, Peter K., Eaton, Amanda, Go, Eden P., Sutherland, Laura L., Scearce, Richard M., Barouch, Dan H., Zhang, Ruijun, Von Holle, Tarra, Overman, R. Glenn, Anasti, Kara, Sanders, Rogier W., Moody, M. Anthony, Kepler, Thomas B., Korber, Bette, Desaire, Heather, Santra, Sampa, Letvin, Norman L., Nabel, Gary J., Montefiori, David C., Tomaras, Georgia D., Liao, Hua-Xin, Alam, S. Munir, Danishefsky, Samuel J., Haynes, Barton F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408352/
https://ncbi.nlm.nih.gov/pubmed/28249163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.003
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