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The P2X7 receptor links mechanical strain to cytokine IL-6 upregulation and release in neurons and astrocytes
BACKGROUND: Mechanical strain in neural tissues can lead to the upregulation and release of multiple cytokines including IL-6. In the retina, the mechanosensitive release of ATP can autostimulate P2X7 receptors on both retinal ganglion cell neurons and optic nerve head astrocytes. Here we asked whet...
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| Publié dans: | J Neurochem |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5408351/ https://ncbi.nlm.nih.gov/pubmed/28244110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13998 |
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