Polygenic Risk Assessment Reveals Pleiotropy between Sarcoidosis and Inflammatory Disorders in the Context of Genetic Ancestry

Sarcoidosis is a complex disease of unknown etiology characterized by the presence of granulomatous inflammation. Though various immune system pathways have been implicated in disease, the relationship between the genetic determinants of sarcoidosis and other inflammatory disorders has not been char...

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Pubblicato in:Genes Immun
Autori principali: Lareau, Caleb A., DeWeese, Colby F., Adrianto, Indra, Lessard, Christopher J., Gaffney, Patrick M., Iannuzzi, Michael C., Rybicki, Benjamin A., Levin, Albert M., Montgomery, Courtney G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407914/
https://ncbi.nlm.nih.gov/pubmed/28275240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2017.3
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