Genome-wide association study of ocular sarcoidosis confirms HLA associations and implicates barrier function and autoimmunity in African Americans

PURPOSE: Identify genes associated with ocular sarcoidosis (OS). METHODS: We genotyped 1.1 million genetic variants to identify significant OS associations, defined as those that achieved p<5×10(−8) in a genome-wide comparison of OS cases to healthy controls in our European- or African-American c...

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Vydáno v:Ocul Immunol Inflamm
Hlavní autoři: Garman, Lori, Pezant, Nathan, Pastori, Ambra, Savoy, Kathryn A., Li, Chuang, Levin, Albert M., Iannuzzi, Michael C., Rybicki, Benjamin A., Adrianto, Indra, Montgomery, Courtney G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483204/
https://ncbi.nlm.nih.gov/pubmed/32141793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09273948.2019.1705985
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