Admixture Fine-Mapping in African Americans Implicates XAF1 as a Possible Sarcoidosis Risk Gene

Sarcoidosis is a complex, multi-organ granulomatous disease with a likely genetic component. West African ancestry confers a higher risk for sarcoidosis than European ancestry. Admixture mapping provides the most direct method to locate genes that underlie such ethnic variation in disease risk. We s...

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Detalhes bibliográficos
Main Authors: Levin, Albert M., Iannuzzi, Michael C., Montgomery, Courtney G., Trudeau, Sheri, Datta, Indrani, Adrianto, Indra, Chitale, Dhananjay A., McKeigue, Paul, Rybicki, Benjamin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963923/
https://ncbi.nlm.nih.gov/pubmed/24663488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092646
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