Performance of HLA allele prediction methods in African Americans for class II genes HLA-DRB1, −DQB1, and –DPB1

BACKGROUND: The expense of human leukocyte antigen (HLA) allele genotyping has motivated the development of imputation methods that use dense single nucleotide polymorphism (SNP) genotype data and the region’s haplotype structure, but the performance of these methods in admixed populations (such as...

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Detalhes bibliográficos
Main Authors: Levin, Albert M, Adrianto, Indra, Datta, Indrani, Iannuzzi, Michael C, Trudeau, Sheri, McKeigue, Paul, Montgomery, Courtney G, Rybicki, Benjamin A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074844/
https://ncbi.nlm.nih.gov/pubmed/24935557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-15-72
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