Performance of HLA allele prediction methods in African Americans for class II genes HLA-DRB1, −DQB1, and –DPB1

BACKGROUND: The expense of human leukocyte antigen (HLA) allele genotyping has motivated the development of imputation methods that use dense single nucleotide polymorphism (SNP) genotype data and the region’s haplotype structure, but the performance of these methods in admixed populations (such as...

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Bibliographic Details
Main Authors: Levin, Albert M, Adrianto, Indra, Datta, Indrani, Iannuzzi, Michael C, Trudeau, Sheri, McKeigue, Paul, Montgomery, Courtney G, Rybicki, Benjamin A
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074844/
https://ncbi.nlm.nih.gov/pubmed/24935557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-15-72
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