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Polygenic Risk Assessment Reveals Pleiotropy between Sarcoidosis and Inflammatory Disorders in the Context of Genetic Ancestry

Sarcoidosis is a complex disease of unknown etiology characterized by the presence of granulomatous inflammation. Though various immune system pathways have been implicated in disease, the relationship between the genetic determinants of sarcoidosis and other inflammatory disorders has not been char...

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Publicat a:Genes Immun
Autors principals: Lareau, Caleb A., DeWeese, Colby F., Adrianto, Indra, Lessard, Christopher J., Gaffney, Patrick M., Iannuzzi, Michael C., Rybicki, Benjamin A., Levin, Albert M., Montgomery, Courtney G.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407914/
https://ncbi.nlm.nih.gov/pubmed/28275240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2017.3
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