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Polygenic Risk Assessment Reveals Pleiotropy between Sarcoidosis and Inflammatory Disorders in the Context of Genetic Ancestry

Sarcoidosis is a complex disease of unknown etiology characterized by the presence of granulomatous inflammation. Though various immune system pathways have been implicated in disease, the relationship between the genetic determinants of sarcoidosis and other inflammatory disorders has not been char...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: Lareau, Caleb A., DeWeese, Colby F., Adrianto, Indra, Lessard, Christopher J., Gaffney, Patrick M., Iannuzzi, Michael C., Rybicki, Benjamin A., Levin, Albert M., Montgomery, Courtney G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407914/
https://ncbi.nlm.nih.gov/pubmed/28275240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2017.3
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