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Multiple Aggregation Pathways in Human γS-Crystallin and Its Aggregation-Prone G18V Variant
PURPOSE: Cataract results from the formation of light-scattering precipitates due to point mutations or accumulated damage in the structural crystallins of the eye lens. Although excised cataracts are predominantly amorphous, in vitro studies show that crystallins are capable of adopting a variety o...
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| 發表在: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Association for Research in Vision and Ophthalmology
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5407245/ https://ncbi.nlm.nih.gov/pubmed/28444328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20621 |
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