Multiple Aggregation Pathways in Human γS-Crystallin and Its Aggregation-Prone G18V Variant

PURPOSE: Cataract results from the formation of light-scattering precipitates due to point mutations or accumulated damage in the structural crystallins of the eye lens. Although excised cataracts are predominantly amorphous, in vitro studies show that crystallins are capable of adopting a variety o...

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Detaylı Bibliyografya
Yayımlandı:Invest Ophthalmol Vis Sci
Asıl Yazarlar: Roskamp, Kyle W., Montelongo, David M., Anorma, Chelsea D., Bandak, Diana N., Chua, Janine A., Malecha, Kurtis T., Martin, Rachel W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Association for Research in Vision and Ophthalmology 2017
Konular:
Lens
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407245/
https://ncbi.nlm.nih.gov/pubmed/28444328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20621
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