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Exploring the Aggregation Propensity of γS-crystallin Protein Variants Using Two Dimensional Spectroscopic Tools

The formation of amyloid fibrils is associated with many 20 serious diseases as well as diverse biological functions. Despite the importance of these aggregates, predicting the aggregation propensity of a particular sequence is a major challenge. We report a joint 2D Nuclear Magnetic Resonance (NMR)...

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Bibliografiske detaljer
Main Authors: Jiang, Jun, Golchert, Kory J., Kingsley, Carolyn N., Brubaker, William D., Martin, Rachel W., Mukamel, Shaul
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946429/
https://ncbi.nlm.nih.gov/pubmed/24219230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp408000k
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