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Exploring the Aggregation Propensity of γS-crystallin Protein Variants Using Two Dimensional Spectroscopic Tools

The formation of amyloid fibrils is associated with many 20 serious diseases as well as diverse biological functions. Despite the importance of these aggregates, predicting the aggregation propensity of a particular sequence is a major challenge. We report a joint 2D Nuclear Magnetic Resonance (NMR)...

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Detalhes bibliográficos
Main Authors: Jiang, Jun, Golchert, Kory J., Kingsley, Carolyn N., Brubaker, William D., Martin, Rachel W., Mukamel, Shaul
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946429/
https://ncbi.nlm.nih.gov/pubmed/24219230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp408000k
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