Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor Ly-GDI in platelet function: a spatial systems approach

On activation at sites of vascular injury, platelets undergo morphological alterations essential to hemostasis via cytoskeletal reorganizations driven by the Rho GTPases Rac1, Cdc42, and RhoA. Here we investigate roles for Rho-specific guanine nucleotide dissociation inhibitor proteins (RhoGDIs) in...

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Pubblicato in:Am J Physiol Cell Physiol
Autori principali: Ngo, Anh T. P., Thierheimer, Marisa L. D., Babur, Özgün, Rocheleau, Anne D., Huang, Tao, Pang, Jiaqing, Rigg, Rachel A., Mitrugno, Annachiara, Theodorescu, Dan, Burchard, Julja, Nan, Xiaolin, Demir, Emek, McCarty, Owen J. T., Aslan, Joseph E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407014/
https://ncbi.nlm.nih.gov/pubmed/28148498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00274.2016
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