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Potentiation of TRAP-6-induced platelet dense granule release by blockade of P2Y(12) signaling with MRS2395
The release of ADP from platelet dense granules and its binding to platelet P2Y(12) receptors is key to amplifying the initial haemostatic response and propagating thrombus formation. P2Y(12) has thus emerged as a therapeutic target to safely and effectively prevent secondary thrombotic events in pa...
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| Publicado no: | Platelets |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6155984/ https://ncbi.nlm.nih.gov/pubmed/28523947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09537104.2017.1316482 |
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