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Potentiation of TRAP-6-induced platelet dense granule release by blockade of P2Y(12) signaling with MRS2395
The release of ADP from platelet dense granules and its binding to platelet P2Y(12) receptors is key to amplifying the initial haemostatic response and propagating thrombus formation. P2Y(12) has thus emerged as a therapeutic target to safely and effectively prevent secondary thrombotic events in pa...
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| 出版年: | Platelets |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6155984/ https://ncbi.nlm.nih.gov/pubmed/28523947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09537104.2017.1316482 |
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