Potentiation of TRAP-6-induced platelet dense granule release by blockade of P2Y(12) signaling with MRS2395

The release of ADP from platelet dense granules and its binding to platelet P2Y(12) receptors is key to amplifying the initial haemostatic response and propagating thrombus formation. P2Y(12) has thus emerged as a therapeutic target to safely and effectively prevent secondary thrombotic events in pa...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Platelets
Huvudupphovsmän: Mitrugno, Annachiara, Rigg, Rachel A., Laschober, Nicole B., Ngo, Anh T.P., Pang, Jiaqing, Williams, Craig D., Aslan, Joseph E., McCarty, Owen J.T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155984/
https://ncbi.nlm.nih.gov/pubmed/28523947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09537104.2017.1316482
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk