Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor Ly-GDI in platelet function: a spatial systems approach

On activation at sites of vascular injury, platelets undergo morphological alterations essential to hemostasis via cytoskeletal reorganizations driven by the Rho GTPases Rac1, Cdc42, and RhoA. Here we investigate roles for Rho-specific guanine nucleotide dissociation inhibitor proteins (RhoGDIs) in...

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Udgivet i:Am J Physiol Cell Physiol
Main Authors: Ngo, Anh T. P., Thierheimer, Marisa L. D., Babur, Özgün, Rocheleau, Anne D., Huang, Tao, Pang, Jiaqing, Rigg, Rachel A., Mitrugno, Annachiara, Theodorescu, Dan, Burchard, Julja, Nan, Xiaolin, Demir, Emek, McCarty, Owen J. T., Aslan, Joseph E.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407014/
https://ncbi.nlm.nih.gov/pubmed/28148498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00274.2016
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