Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor Ly-GDI in platelet function: a spatial systems approach

On activation at sites of vascular injury, platelets undergo morphological alterations essential to hemostasis via cytoskeletal reorganizations driven by the Rho GTPases Rac1, Cdc42, and RhoA. Here we investigate roles for Rho-specific guanine nucleotide dissociation inhibitor proteins (RhoGDIs) in...

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Publicado en:Am J Physiol Cell Physiol
Autores principales: Ngo, Anh T. P., Thierheimer, Marisa L. D., Babur, Özgün, Rocheleau, Anne D., Huang, Tao, Pang, Jiaqing, Rigg, Rachel A., Mitrugno, Annachiara, Theodorescu, Dan, Burchard, Julja, Nan, Xiaolin, Demir, Emek, McCarty, Owen J. T., Aslan, Joseph E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407014/
https://ncbi.nlm.nih.gov/pubmed/28148498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00274.2016
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