Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor Ly-GDI in platelet function: a spatial systems approach

On activation at sites of vascular injury, platelets undergo morphological alterations essential to hemostasis via cytoskeletal reorganizations driven by the Rho GTPases Rac1, Cdc42, and RhoA. Here we investigate roles for Rho-specific guanine nucleotide dissociation inhibitor proteins (RhoGDIs) in...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Ngo, Anh T. P., Thierheimer, Marisa L. D., Babur, Özgün, Rocheleau, Anne D., Huang, Tao, Pang, Jiaqing, Rigg, Rachel A., Mitrugno, Annachiara, Theodorescu, Dan, Burchard, Julja, Nan, Xiaolin, Demir, Emek, McCarty, Owen J. T., Aslan, Joseph E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407014/
https://ncbi.nlm.nih.gov/pubmed/28148498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00274.2016
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