DDK Promotes Tumor Chemoresistance and Survival via Multiple Pathways

DBF4-dependent kinase (DDK) is a two-subunit kinase required for initiating DNA replication at individual origins and is composed of CDC7 kinase and its regulatory subunit DBF4. Both subunits are highly expressed in many diverse tumor cell lines and primary tumors, and this is correlated with poor p...

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Detaylı Bibliyografya
Yayımlandı:Neoplasia
Asıl Yazarlar: Sasi, Nanda Kumar, Bhutkar, Arjun, Lanning, Nathan J., MacKeigan, Jeffrey P., Weinreich, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Neoplasia Press 2017
Konular:
Original article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406526/
https://ncbi.nlm.nih.gov/pubmed/28448802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.03.001
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