DDK Promotes Tumor Chemoresistance and Survival via Multiple Pathways

DBF4-dependent kinase (DDK) is a two-subunit kinase required for initiating DNA replication at individual origins and is composed of CDC7 kinase and its regulatory subunit DBF4. Both subunits are highly expressed in many diverse tumor cell lines and primary tumors, and this is correlated with poor p...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Sasi, Nanda Kumar, Bhutkar, Arjun, Lanning, Nathan J., MacKeigan, Jeffrey P., Weinreich, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2017
Assuntos:
Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406526/
https://ncbi.nlm.nih.gov/pubmed/28448802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.03.001
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