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Downregulation of the Mitochondrial Phosphatase PTPMT1 Is Sufficient to Promote Cancer Cell Death

Protein Tyrosine Phosphatase localized to the Mitochondrion 1 (PTPMT1) is a dual specificity phosphatase exclusively localized to the mitochondria, and has recently been shown to be a critical component in the cardiolipin biosynthetic pathway. The downregulation of PTPMT1 in pancreatic beta cells ha...

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Detalhes bibliográficos
Main Authors: Niemi, Natalie M., Lanning, Nathan J., Westrate, Laura M., MacKeigan, Jeffrey P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542197/
https://ncbi.nlm.nih.gov/pubmed/23326511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053803
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