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Persistent Mitochondrial Hyperfusion Promotes G2/M Accumulation and Caspase-Dependent Cell Death

Cancer cells have several hallmarks that define their neoplastic behavior. One is their unabated replicative potential that allows cells to continually proliferate, and thereby contribute to increasing tumor burden. The progression of a cell through the cell cycle is regulated by a series of checkpo...

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Hlavní autoři: Westrate, Laura M., Sayfie, Aaron D., Burgenske, Danielle M., MacKeigan, Jeffrey P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954829/
https://ncbi.nlm.nih.gov/pubmed/24632851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091911
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