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Sensing Enzymatic Activity by Exposure and Selection of DNA-encoded Probes
A sensing approach is described and is applied to encode quantitative enzymatic activity information into DNA sequence populations. The method utilizes DNA-linked peptide substrates as activity probes. Signal detection involves chemical manipulation of a probe population downstream of sample exposur...
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| Publicado en: | Angew Chem Int Ed Engl |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5402352/ https://ncbi.nlm.nih.gov/pubmed/27355201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201603387 |
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