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A Fluorescent Probe for Monitoring PTP-PEST Enzymatic Activity

Phosphatase non-receptor type 12 (PTPN12 or PTP-PEST) is a critical regulator of cell migration, acting as a tumor suppressor in cancer. Decreases in PTP-PEST expression correlate with aggressive phenotypes in hepatocellular carcinoma (HCC). Despite the importance of PTP-PEST in cellular signaling,...

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Udgivet i:Analyst
Main Authors: Casey, Garrett R., Stains, Cliff I.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554172/
https://ncbi.nlm.nih.gov/pubmed/32812952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0an00993h
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